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💊 Coeliac disease, one theory knocked out Scientists in Australia studied immune cells from coeliac patients and found they behaved the same regardless of what triggered them, undercutting one theory of the disease. 🔗 doi.org/10.1126/sciadv.aei3175 #Health #Coeliac #Immunology 🧪
doi.org Gliadin-specific CD4+ T cells exhibit functional diversity independent of TCR usage or epitope specificity
Join us to explore whether transposable elements can be harnessed to uncover new immunotherapy targets for childhood AML. A fully funded PhD combining cancer genomics, epigenetics and immunology, with access to unique paediatric AML patient datasets and samples. Join us at Barts Cancer Institute! 👇
Gut Microbiome & Vaccine Responses: Study identifies a gut microbe-immune pathway that primes some for stronger vaccine inflammation. This may help explain individual differences and opens possibilities for mechanisms. doi.org/10.1126/scie...
doi.org The human gut microbiome primes fever after vaccination
#Medsky🧪 #IDsky #immunosky #vaccinesmatter #publichealth XFG-adapted mRNA vaccination significantly ⏫️ neutralising activity against all tested #SARSCoV2 variants, boosting cross-reactive humoral immunity across multiple lineages.According to early immunogenicity data www.medrxiv.org/content/10.6...
medrxiv.org Effects of XFG-adapted mRNA vaccination on SARS-CoV-2 variant neutralisation
Something worth noting. It's not that everyone is getting sick right now with COVID (it's part of it), but more so how COVID sicknesses have screwed with our immune systems. It's why sicknesses for a lot of people tend to be harsher than atypical. Vaccination hesitation to typical seasonal stuff>
"SARS-CoV-2 is linked to “an unusually high level of ‘indiscriminate’ killing of T cells,”6 says Leitner, adding that this observation is “reminiscent of” measles, which can cause immune amnesia by depleting memory B cells"
A new plant-bacteria immunological connection in the first preprint of our group at @mpi-bio-fml.bsky.social @plantevolution.bsky.social! Straight from the top of Mt. Olympus ⛰️🦅 Led by Eirik @eiriklag.bsky.social, in collaboration with @geminiteamlab.bsky.social www.biorxiv.org/content/10.6...
Stanford researchers, >220 lung donors. SARS-CoV-2 infected lung epithelium and activated local virus-specific resident T cells. Boosting them cut viral RNA 36% and infectious virus 45%, showing local lung immunity can restrain infection. www.nature.com/articles/s41...
nature.com
"The immune system is like a memory bank. Every #vaccination or recovery from infection is a deposit that's filed away. Then when someone encounters certain pathogens in the future, the immune system remembers how to fight them off. "But #measles can wipe out that memory bank, erasing as much as 73% of someone's hard-won immunity..." cidrap.umn.edu/measles/measles…
cidrap.umn.edu Measles can cast a long shadow, even after an apparent full recovery -
Gut microbes shape the body’s response to vaccination. Researchers led by Ruth Ley discovered that the human gut microbiome may help determine how strongly the immune system reacts to vaccination, with bacterial flagellins contributing to inflammatory responses: www.bio.mpg.de/569449/news_...
bio.mpg.de Gut microbes help set the body’s response to vaccination
Got the flu and COVID vaccines yesterday and they're currently going to town on me like:
COVID jab acquired. Right in a bruise!
From Germany Brain-binding auto-antibodies in subjects with and without post-COVID-syndrome after SARS-CoV-2 infection www.sciencedirect.com/science/arti... Screenshot from latest Science for ME weekly update #LongCovid #NeuroPASC #PASC
From Ireland Characterizing Host Inflammatory Bioprofiles in People With Postacute Sequelae SARS-CoV-2 Infection (PASC) onlinelibrary.wiley.com/doi/10.1155/... Screenshot from latest Science for ME weekly update #LongCovid #PASC #PwLC #postcovid #postcovid19
I got 4 vaccines yesterday. That's right, bitches. I win the immune system olympiad. Catch up.
Im literally covered in hives? Its so weird the physiological response to stress
COVID and Flu vaxxed. 💉
🎯🧵by Vipin M. Vashishtha aka @vipintukur on XTwitter: "#LongCOVID may not be one disease—but several biological phenotypes hiding under one name. ➡️ In 356 people with PASC, researchers measured 57 biomarkers across 8 biological pathways and identified six..." threadreaderapp.com/thread/21070...
Got mine yesterday
'Collectively, this study elucidates that nozzle- and fiber-elicited neutralizing antibodies impair phage therapy via dual synergistic mechanisms, which offers novel insights into the multifaceted modulation of phage-specific antibodies against phage therapeutic efficacy.'
journals.plos.org Antibodies targeting phage fiber and nozzle proteins impair Acinetobacter baumannii phage therapy by blocking infection and promoting immune clearance
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